Unai Emery put Rugani on his transfer wish list this summer as he looked to bolster his defence ahead of the 2019/20 campaign.
But it was David Luiz who rocked up at the Emirates instead as Arsenal hammered out a shock £8m deadline day deal with Chelsea.
Rugani now looks set for Roma, with talks between their sporting director Gianluca Petrachi, Juventus chief Fabio Paratici and potentially the centre-back’s agent taking place on Tuesday.
It seems Roma will have to go one step further than Arsenal were prepared to in order to get the Italy international on board.
According to Turin-based newspaper Tuttosport, the Gunners were not willing to agree to a clause that would almost guarantee they buy Rugani.
Arsenal would have had to hand over around £28m (€30m) in order to take the 25-year-old off Juventus’ hands on a permanent basis if a series of conditions were met.
However, the likes of Raul Sanllehi were opposed to the idea of sanctioning such an agreement for former Empoli ace Rugani.
That decision came after Arsenal had already committed to paying £72m for club-record signing Nicolas Pepe, £27m for William Saliba, £25m for Kieran Tierney, £6m for Gabriel Martinelli and a £5m loan fee for Dani Ceballos.
Arsenal will instead pay £4m this year and £4m in 12 months’ time to Chelsea for veteran centre-back Luiz.
The Brazilian was an unused substitute for Sunday’s 1-0 win over Newcastle as Emery went with Calum Chambers and Sokratis Papastathopoulos from the off.
Emery explained his thinking on leaving Luiz on the bench after Pierre-Emerick Aubameyang’s strike sealed an opening weekend three points fro Arsenal.
“I explained yesterday that the circumstances are different,” Emery said.
“David Luiz did pre-season with another team and he is okay to play physically but he only trained completely with us yesterday.
“On Friday he did 30 minutes with us. I was thinking to give them confidence to work together because they were working well together, Sokratis and Chambers.
“Nicolas Pepe came one week ago and physically he needs to get his best fitness to be ready to play 100 per cent for 90 minutes. I think that today 20 minutes is good for him.
“And Ceballos is in the middle because he came before Pepe but he got an injury and he stopped training. But he needs to know the Premier League, so today was important for him and for us.
“I also used Reiss Nelson and [Joe] Willock because they deserved to be with us and to give them confidence can help us.
“It’s the same with Martinelli, he played the last 10 minutes because he deserved it.”
Next up for Arsenal is Saturday’s lunch-time kick-off against Sean Dyche’s Burnley.
Emery led the north Londoners to a pair of 3-1 Premier League wins over the Clarets last season.